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Role of BDNF/ProBDNF Imbalance in Postoperative Cognitive Dysfunction by Modulating Synaptic Plasticity in Aged Mice

Postoperative cognitive dysfunction (POCD) is a disturbing neurological complication in patients undergoing anesthesia and surgical procedures. Brain-derived neurotrophic factor (BDNF) and its precursor proBDNF binding to their corresponding receptors tyrosine kinase (TrkB) and p75 neurotrophin rece...

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Detalles Bibliográficos
Autores principales: Xue, Ziyi, Shui, Min, Lin, Xiaowan, Sun, Yi, Liu, Jianhui, Wei, Changwei, Wu, Anshi, Li, Tianzuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975148/
https://www.ncbi.nlm.nih.gov/pubmed/35370607
http://dx.doi.org/10.3389/fnagi.2022.780972