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CD8(+) T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19

A central feature of the SARS-CoV-2 pandemic is that some individuals become severely ill or die, whereas others have only a mild disease course or are asymptomatic. Here, we report the development of an improved multimeric αβ T cell staining reagent platform, with each maxi-ferritin “spheromer” dis...

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Detalles Bibliográficos
Autores principales: Mallajosyula, Vamsee, Ganjavi, Conner, Chakraborty, Saborni, McSween, Alana M., Pavlovitch-Bedzyk, Ana Jimena, Wilhelmy, Julie, Nau, Allison, Manohar, Monali, Nadeau, Kari C., Davis, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975171/
https://www.ncbi.nlm.nih.gov/pubmed/34210785
http://dx.doi.org/10.1126/sciimmunol.abg5669