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Synthetic reconstruction of the hunchback promoter specifies the role of Bicoid, Zelda and Hunchback in the dynamics of its transcription

For over 40 years, the Bicoid-hunchback (Bcd-hb) system in the fruit fly embryo has been used as a model to study how positional information in morphogen concentration gradients is robustly translated into step-like responses. A body of quantitative comparisons between theory and experiment have sin...

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Detalles Bibliográficos
Autores principales: Fernandes, Gonçalo, Tran, Huy, Andrieu, Maxime, Diaw, Youssoupha, Perez Romero, Carmina, Fradin, Cécile, Coppey, Mathieu, Walczak, Aleksandra M, Dostatni, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975551/
https://www.ncbi.nlm.nih.gov/pubmed/35363606
http://dx.doi.org/10.7554/eLife.74509