Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies

PML nuclear bodies (PML-NBs) are dynamic interchromosomal macromolecular complexes implicated in epigenetic regulation as well as antiviral defense. During herpesvirus infection, PML-NBs induce epigenetic silencing of viral genomes, however, this defense is antagonized by viral regulatory proteins s...

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Detalles Bibliográficos
Autores principales: Scherer, Myriam, Read, Clarissa, Neusser, Gregor, Kranz, Christine, Kuderna, Anna K, Müller, Regina, Full, Florian, Wörz, Sonja, Reichel, Anna, Schilling, Eva-Maria, Walther, Paul, Stamminger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975554/
https://www.ncbi.nlm.nih.gov/pubmed/35319461
http://dx.doi.org/10.7554/eLife.73006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975554/
https://www.ncbi.nlm.nih.gov/pubmed/35319461
http://dx.doi.org/10.7554/eLife.73006

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