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Extracellular Cardiolipin Modulates Select Immune Functions of Astrocytes in Toll-Like Receptor (TLR) 4-Dependent Manner

Alzheimer's disease (AD) is characterized by chronic neuroinflammation, which is partially mediated by dysregulated functions of glial cells. Cardiolipin (CL) is a phospholipid normally confined to the inner mitochondrial membrane; however, it has been detected in human sera, indicating that it...

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Detalles Bibliográficos
Autores principales: Murray, Taryn E., Wenzel, Tyler J., Simtchouk, Svetlana, Greuel, Bridget K., Gibon, Julien, Klegeris, Andis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975658/
https://www.ncbi.nlm.nih.gov/pubmed/35369030
http://dx.doi.org/10.1155/2022/9946439