Cargando…

The Beneficial Effect of IL-12 and IL-18 Transduced Dendritic Cells Stimulated with Tumor Antigens on Generation of an Antitumor Response in a Mouse Colon Carcinoma Model

The main purpose of our study was to determine the effect of dendritic cell (DC) transduction with lentiviral vectors carrying sequences of il18 and/or il12 genes on the level of antitumor activity in vitro and in vivo. We examined the ability of DCs to migrate to the tumor-draining lymph nodes and...

Descripción completa

Detalles Bibliográficos
Autores principales: Mierzejewska, Jagoda, Węgierek-Ciura, Katarzyna, Rossowska, Joanna, Szczygieł, Agnieszka, Anger-Góra, Natalia, Szermer-Olearnik, Bożena, Geneja, Magdalena, Pajtasz-Piasecka, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975686/
https://www.ncbi.nlm.nih.gov/pubmed/35372586
http://dx.doi.org/10.1155/2022/7508928