LIGHT enhanced bispecific antibody armed T-cells to treat immunotherapy resistant colon cancer

ABSTRACT: Increased tumor infiltrating lymphocytes (TIL) are associated with improved patient responses to immunotherapy. As a result, there is interest in enhancing lymphocyte trafficking particularly to colon cancers since the majority are checkpoint blockade-resistant and microsatellite stable. H...

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Detalles Bibliográficos
Autores principales: Qiao, Guilin, Kone, Lyonell B., Phillips, Evan H., Lee, Steve Seung-Young, Brown, Grace E., Khetani, Salman R., Thakur, Archana, Lum, Lawrence G., Prabhakar, Bellur S., Maker, Ajay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975745/
https://www.ncbi.nlm.nih.gov/pubmed/35177811
http://dx.doi.org/10.1038/s41388-022-02209-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975745/
https://www.ncbi.nlm.nih.gov/pubmed/35177811
http://dx.doi.org/10.1038/s41388-022-02209-w

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