Population Pharmacokinetic Analysis to Assist Dose Selection of the l-Ornithine Salt of Phenylacetic Acid

BACKGROUND AND OBJECTIVE: l-Ornithine phenylacetate is an intravenous formulation of the l-ornithine salt of phenylacetic acid under development for the treatment of hepatic encephalopathy. Very limited clinical data in patients are available, with a phase II study in target patients not designed fo...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofeng, Vilchez, Regis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975757/
https://www.ncbi.nlm.nih.gov/pubmed/34786649
http://dx.doi.org/10.1007/s40262-021-01075-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975757/
https://www.ncbi.nlm.nih.gov/pubmed/34786649
http://dx.doi.org/10.1007/s40262-021-01075-1

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