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Population Pharmacokinetic Analysis to Assist Dose Selection of the l-Ornithine Salt of Phenylacetic Acid

BACKGROUND AND OBJECTIVE: l-Ornithine phenylacetate is an intravenous formulation of the l-ornithine salt of phenylacetic acid under development for the treatment of hepatic encephalopathy. Very limited clinical data in patients are available, with a phase II study in target patients not designed fo...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaofeng, Vilchez, Regis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975757/ https://www.ncbi.nlm.nih.gov/pubmed/34786649 http://dx.doi.org/10.1007/s40262-021-01075-1

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