Cargando…

AF2Complex predicts direct physical interactions in multimeric proteins with deep learning

Accurate descriptions of protein-protein interactions are essential for understanding biological systems. Remarkably accurate atomic structures have been recently computed for individual proteins by AlphaFold2 (AF2). Here, we demonstrate that the same neural network models from AF2 developed for sin...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Mu, Nakajima An, Davi, Parks, Jerry M., Skolnick, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975832/
https://www.ncbi.nlm.nih.gov/pubmed/35365655
http://dx.doi.org/10.1038/s41467-022-29394-2