A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platforms

Phage display technology allows for rapid selection of antibodies from the large repertoire of human antibody fragments displayed on phages. However, antibody fragments should be converted to IgG for biological characterizations and affinity of antibodies obtained from phage display library is frequ...

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Detalles Bibliográficos
Autores principales: Jin, Yu-jia, Yu, Diao, Tian, Xiao-long, Li, Hui-xian, Zhou, Xiao-chao, Kong, Yu, Zhang, Wei, Zhang, Lu, Lei, Cheng, Yang, Zhen-lin, Tu, Chao, Wu, Yan-ling, Ying, Tian-lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975860/
https://www.ncbi.nlm.nih.gov/pubmed/34234269
http://dx.doi.org/10.1038/s41401-021-00707-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975860/
https://www.ncbi.nlm.nih.gov/pubmed/34234269
http://dx.doi.org/10.1038/s41401-021-00707-3

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