PI3Kγ stimulates a high molecular weight form of myosin light chain kinase to promote myeloid cell adhesion and tumor inflammation

Myeloid cells play key roles in cancer immune suppression and tumor progression. In response to tumor derived factors, circulating monocytes and granulocytes extravasate into the tumor parenchyma where they stimulate angiogenesis, immune suppression and tumor progression. Chemokines, cytokines and i...

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Detalles Bibliográficos
Autores principales: Schmid, Michael C., Kang, Sang Won, Chen, Hui, Paradise, Marc, Ghebremedhin, Anghesom, Kaneda, Megan M., Chin, Shao-Ming, Do, Anh, Watterson, D. Martin, Varner, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975949/
https://www.ncbi.nlm.nih.gov/pubmed/35365657
http://dx.doi.org/10.1038/s41467-022-29471-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975949/
https://www.ncbi.nlm.nih.gov/pubmed/35365657
http://dx.doi.org/10.1038/s41467-022-29471-6

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