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A deep learning model (FociRad) for automated detection of γ-H2AX foci and radiation dose estimation

DNA double-strand breaks (DSBs) are the most lethal form of damage to cells from irradiation. γ-H2AX (phosphorylated form of H2AX histone variant) has become one of the most reliable and sensitive biomarkers of DNA DSBs. However, the γ-H2AX foci assay still has limitations in the time consumed for m...

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Detalles Bibliográficos
Autores principales: Wanotayan, Rujira, Chousangsuntorn, Khaisang, Petisiwaveth, Phasit, Anuttra, Thunchanok, Lertchanyaphan, Waritsara, Jaikuna, Tanwiwat, Jangpatarapongsa, Kulachart, Uttayarat, Pimpon, Tongloy, Teerawat, Chousangsuntorn, Chousak, Boonsang, Siridech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975967/
https://www.ncbi.nlm.nih.gov/pubmed/35365702
http://dx.doi.org/10.1038/s41598-022-09180-2