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High glucose concentrations induce oxidative stress by inhibiting Nrf2 expression in rat Müller retinal cells in vitro

Diabetic retinopathy (DR) is a complication of diabetes. Several studies have implicated oxidative stress as a fundamental factor in the progression of the disease. The nuclear factor erythroid-2-related factor 2 (Nrf2) is one of the main regulators of redox homeostasis. Glia Müller cells (MC) maint...

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Detalles Bibliográficos
Autores principales: Albert-Garay, Jesús Silvestre, Riesgo-Escovar, Juan Rafael, Salceda, Rocío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975969/
https://www.ncbi.nlm.nih.gov/pubmed/35075205
http://dx.doi.org/10.1038/s41598-022-05284-x