Enantioselective functionalization at the C4 position of pyridinium salts through NHC catalysis

A catalytic method for the enantioselective and C4-selective functionalization of pyridine derivatives is yet to be developed. Herein, we report an efficient method for the asymmetric β-pyridylations of enals that involve N-heterocyclic carbene (NHC) catalysis with excellent control over enantiosele...

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Detalles Bibliográficos
Autores principales: Choi, Hangyeol, Mathi, Gangadhar Rao, Hong, Seonghyeok, Hong, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975994/
https://www.ncbi.nlm.nih.gov/pubmed/35365667
http://dx.doi.org/10.1038/s41467-022-29462-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975994/
https://www.ncbi.nlm.nih.gov/pubmed/35365667
http://dx.doi.org/10.1038/s41467-022-29462-7

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