Cargando…

Inhibition of RIPK1 by ZJU-37 promotes oligodendrocyte progenitor proliferation and remyelination via NF-κB pathway

Receptor interacting serine/threonine protein kinase 1 (RIPK1) activation and necroptosis have been genetically and mechanistically linked with human multiple sclerosis and neurodegenerative diseases for which demyelination is a common key pathology. Demyelination can be healed through remyelination...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Xiao-Ru, Yang, Shu-Ying, Zheng, Shuang-Shuang, Yan, Huan-Huan, Gu, Hui-Min, Wang, Fan, Wu, Yang, Dong, Zhao-Jun, Wang, Di-Xian, Wang, Yue, Meng, Xianhui, Sun, Jie, Xia, Hong-Guang, Zhao, Jing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975999/
https://www.ncbi.nlm.nih.gov/pubmed/35365618
http://dx.doi.org/10.1038/s41420-022-00929-2