Identification and validation of ecto-5' nucleotidase as an immunotherapeutic target in multiple myeloma

Interaction of plasmacytoid dendritic cells (pDCs) with multiple myeloma (MM) cells, T- or NK-effector cells in the bone marrow (BM) microenvironment induces tumor cell growth, as well as inhibits innate and adaptive immune responses. Defining pDC-MM interaction-triggered immunosuppressive mechanism...

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Detalles Bibliográficos
Autores principales: Ray, Arghya, Song, Yan, Du, Ting, Buon, Leutz, Tai, Yu-Tzu, Chauhan, Dharminder, Anderson, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976016/
https://www.ncbi.nlm.nih.gov/pubmed/35365613
http://dx.doi.org/10.1038/s41408-022-00635-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976016/
https://www.ncbi.nlm.nih.gov/pubmed/35365613
http://dx.doi.org/10.1038/s41408-022-00635-3

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