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Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy

Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression...

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Detalles Bibliográficos
Autores principales: Zhao, Mingming, Wei, Haoran, Li, Chenze, Zhan, Rui, Liu, Changjie, Gao, Jianing, Yi, Yaodong, Cui, Xiao, Shan, Wenxin, Ji, Liang, Pan, Bing, Cheng, Si, Song, Moshi, Sun, Haipeng, Jiang, Huidi, Cai, Jun, Garcia-Barrio, Minerva T., Chen, Y. Eugene, Meng, Xiangbao, Dong, Erdan, Wang, Dao Wen, Zheng, Lemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976029/
https://www.ncbi.nlm.nih.gov/pubmed/35365608
http://dx.doi.org/10.1038/s41467-022-29060-7