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The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis
Sepsis is a heterogeneous syndrome induced by a dysregulated host response to infection. Glycolysis plays a role in maintaining the immune function of macrophages, which is crucial for severely septic patients. However, how the pathways that link glycolysis and macrophages are regulated is still lar...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976055/ https://www.ncbi.nlm.nih.gov/pubmed/34983946 http://dx.doi.org/10.1038/s41423-021-00806-5 |