The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis

Sepsis is a heterogeneous syndrome induced by a dysregulated host response to infection. Glycolysis plays a role in maintaining the immune function of macrophages, which is crucial for severely septic patients. However, how the pathways that link glycolysis and macrophages are regulated is still lar...

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Detalles Bibliográficos
Autores principales: Yuan, Yuan, Fan, Guangjian, Liu, Yuqi, Liu, Lu, Zhang, Tong, Liu, Pengfei, Tu, Qing, Zhang, Xinyi, Luo, Shiyuan, Yao, Liangfang, Chen, Feng, Li, Jingbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976055/
https://www.ncbi.nlm.nih.gov/pubmed/34983946
http://dx.doi.org/10.1038/s41423-021-00806-5

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