Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time

Genetic mutations have long been recognized as drivers of cancer drug resistance, but recent work has defined additional non-genetic mechanisms of plasticity, wherein cancer cells assume a drug resistant phenotype marked by altered epigenetic and transcriptional states. Currently, little is known ab...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Tong, Junge, Jason A., Delfarah, Alireza, Lu, Yi-Tsung, Arnesano, Cosimo, Iqbal, Maheen, Delijani, Kevin, Hsieh, Tien-Chan, Hodara, Emmanuelle, Mehta, Hemal H., Cohen, Pinchas, Graham, Nicholas A., Fraser, Scott E., Goldkorn, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976067/
https://www.ncbi.nlm.nih.gov/pubmed/35365706
http://dx.doi.org/10.1038/s41598-022-09438-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976067/
https://www.ncbi.nlm.nih.gov/pubmed/35365706
http://dx.doi.org/10.1038/s41598-022-09438-9

Ejemplares similares