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Bladder cancer cells shift rapidly and spontaneously to cisplatin-resistant oxidative phosphorylation that is trackable in real time
Genetic mutations have long been recognized as drivers of cancer drug resistance, but recent work has defined additional non-genetic mechanisms of plasticity, wherein cancer cells assume a drug resistant phenotype marked by altered epigenetic and transcriptional states. Currently, little is known ab...
Autores principales: | Xu, Tong, Junge, Jason A., Delfarah, Alireza, Lu, Yi-Tsung, Arnesano, Cosimo, Iqbal, Maheen, Delijani, Kevin, Hsieh, Tien-Chan, Hodara, Emmanuelle, Mehta, Hemal H., Cohen, Pinchas, Graham, Nicholas A., Fraser, Scott E., Goldkorn, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976067/ https://www.ncbi.nlm.nih.gov/pubmed/35365706 http://dx.doi.org/10.1038/s41598-022-09438-9 |
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