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Structural basis of FPR2 in recognition of Aβ(42) and neuroprotection by humanin
Formyl peptide receptor 2 (FPR2) has been shown to mediate the cytotoxic effects of the β amyloid peptide Aβ(42) and serves as a receptor for humanin, a peptide that protects neuronal cells from damage by Aβ(42), implying its involvement in the pathogenesis of Alzheimer’s disease (AD). However, the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976073/ https://www.ncbi.nlm.nih.gov/pubmed/35365641 http://dx.doi.org/10.1038/s41467-022-29361-x |