Structural basis of FPR2 in recognition of Aβ(42) and neuroprotection by humanin

Formyl peptide receptor 2 (FPR2) has been shown to mediate the cytotoxic effects of the β amyloid peptide Aβ(42) and serves as a receptor for humanin, a peptide that protects neuronal cells from damage by Aβ(42), implying its involvement in the pathogenesis of Alzheimer’s disease (AD). However, the...

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Detalles Bibliográficos
Autores principales: Zhu, Ya, Lin, Xiaowen, Zong, Xin, Han, Shuo, Wang, Mu, Su, Yuxuan, Ma, Limin, Chu, Xiaojing, Yi, Cuiying, Zhao, Qiang, Wu, Beili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976073/
https://www.ncbi.nlm.nih.gov/pubmed/35365641
http://dx.doi.org/10.1038/s41467-022-29361-x

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