Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits

microRNA-592 (miR-592) has been linked to neurogenesis, but the influence of miR-592 knockout in vivo remains unknown. Here, we report that miR-592 knockout represses IPC-to-mature neuron transition, impairs motor coordination and reduces social interaction. Combining the RNA-seq and tandem mass tag...

Descripción completa

Detalles Bibliográficos
Autores principales: Fu, Yu, Zhou, Yang, Zhang, Yuan-Lin, Zhao, Bo, Zhang, Xing-Liao, Zhang, Wan-Ting, Lu, Yi-Jun, Lu, Aiping, Zhang, Jun, Zhang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976077/
https://www.ncbi.nlm.nih.gov/pubmed/35365601
http://dx.doi.org/10.1038/s41419-022-04721-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976077/
https://www.ncbi.nlm.nih.gov/pubmed/35365601
http://dx.doi.org/10.1038/s41419-022-04721-z

Ejemplares similares