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Evaluation of Jumonji C lysine demethylase substrate preference to guide identification of in vitro substrates
Within the realm of lysine methylation, the discovery of lysine methyltransferase (KMTs) substrates has been burgeoning because of established systematic substrate screening protocols. Here, we describe a protocol enabling the systematic identification of JmjC KDM substrate preference and in vitro s...
Autores principales: | Hoekstra, Matthew, Chopra, Anand, Willmore, William G., Biggar, Kyle K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976124/ https://www.ncbi.nlm.nih.gov/pubmed/35378885 http://dx.doi.org/10.1016/j.xpro.2022.101271 |
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