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RNA chain length and stoichiometry govern surface tension and stability of protein-RNA condensates

Proteomic studies have shown that cellular condensates are frequently enriched in diverse RNA molecules, which is suggestive of mechanistic links between phase separation and transcriptional activities. Here, we report a systematic experimental and computational study of thermodynamic landscapes and...

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Detalles Bibliográficos
Autores principales: Laghmach, Rabia, Alshareedah, Ibraheem, Pham, Matthew, Raju, Muralikrishna, Banerjee, Priya R., Potoyan, Davit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976129/
https://www.ncbi.nlm.nih.gov/pubmed/35378855
http://dx.doi.org/10.1016/j.isci.2022.104105