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Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma

Response rates to immune checkpoint blockade (ICB) remain low in oesophageal adenocarcinoma (OAC). Combining ICB with immunostimulatory chemotherapies to boost response rates is an attractive approach for converting ‘cold’ tumours into ‘hot’ tumours. This study profiled immune checkpoint (IC) expres...

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Detalles Bibliográficos
Autores principales: Davern, Maria, Donlon, Noel E., O’ Connell, Fiona, Sheppard, Andrew D., Hayes, Conall, King, Ross, Temperley, Hugo, Butler, Christine, Bhardwaj, Anshul, Moore, Jenny, Bracken-Clarke, Dara, Donohoe, Claire, Ravi, Narayanasamy, Reynolds, John V., Maher, Stephen G., Conroy, Melissa J., Lysaght, Joanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976141/
https://www.ncbi.nlm.nih.gov/pubmed/35366537
http://dx.doi.org/10.1016/j.tranon.2022.101406