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Role of tau deposition in early cognitive decline in Down syndrome

INTRODUCTION: Drawing on the amyloid/tau/neurodegeneration (AT[N]) model, the study examined whether the tau positron emission tomography (PET) biomarker [(18)F]AV‐1451 was associated with episodic memory problems beyond what was predicted by the amyloid beta (Aβ) PET in Down syndrome (DS). METHODS:...

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Detalles Bibliográficos
Autores principales: Hartley, Sigan L., Handen, Benjamin L., Tudorascu, Dana, Lee, Laise, Cohen, Annie, Piro‐Gambetti, Brianna, Zammit, Matthew, Klunk, William, Laymon, Charles, Zaman, Shahid, Ances, Beau M., Sabbagh, Marwan, Christian, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976157/
https://www.ncbi.nlm.nih.gov/pubmed/35386473
http://dx.doi.org/10.1002/dad2.12256