Characteristics and Clinical Implication of UGT1A1 Heterozygous Mutation in Tumor

BACKGROUND: The literature recommends that reduced dosage of CPT-11 should be applied in patients with UGT1A1 homozygous mutations, but the impact of UGT1A1 heterozygous mutations on the adverse reactions of CPT-11 is still not fully clear. METHODS: A total of 107 patients with UGT1A1 heterozygous m...

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Detalles Bibliográficos
Autores principales: LI, Qian, SUN, Tao, ZHANG, Hua, LIU, Wei, XIAO, Yu, SUN, Hongqi, YIN, Wencheng, YAO, Yanhong, GU, Yangchun, LIU, Yan'e, YI, Fumei, WANG, Qiqi, YU, Jinyu, CAO, Baoshan, LIANG, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 中国肺癌杂志编辑部 2022
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976199/
https://www.ncbi.nlm.nih.gov/pubmed/35340156
http://dx.doi.org/10.3779/j.issn.1009-3419.2022.101.07

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976199/
https://www.ncbi.nlm.nih.gov/pubmed/35340156
http://dx.doi.org/10.3779/j.issn.1009-3419.2022.101.07

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