A multi-institutional pilot clinical trial of spectroscopic MRI-guided radiation dose escalation for newly diagnosed glioblastoma

BACKGROUND: Glioblastomas (GBMs) are aggressive brain tumors despite radiation therapy (RT) to 60 Gy and temozolomide (TMZ). Spectroscopic magnetic resonance imaging (sMRI), which measures levels of specific brain metabolites, can delineate regions at high risk for GBM recurrence not visualized on c...

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Detalles Bibliográficos
Autores principales: Ramesh, Karthik, Mellon, Eric A, Gurbani, Saumya S, Weinberg, Brent D, Schreibmann, Eduard, Sheriff, Sulaiman A, Goryawala, Mohammed, de le Fuente, Macarena, Eaton, Bree R, Zhong, Jim, Voloschin, Alfredo D, Sengupta, Soma, Dunbar, Erin M, Holdhoff, Matthias, Barker, Peter B, Maudsley, Andrew A, Kleinberg, Lawrence R, Shim, Hyunsuk, Shu, Hui-Kuo G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976280/
https://www.ncbi.nlm.nih.gov/pubmed/35382436
http://dx.doi.org/10.1093/noajnl/vdac006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976280/
https://www.ncbi.nlm.nih.gov/pubmed/35382436
http://dx.doi.org/10.1093/noajnl/vdac006

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