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The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?
Cellular senescence is a state of irreversible cell cycle arrest that can be induced by a variety of potentially oncogenic stimuli, including DNA damage. Hence, senescence has long been considered to suppress tumorigenesis, acting as a guardian of homeostasis. However, recent studies have revealed t...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976373/ https://www.ncbi.nlm.nih.gov/pubmed/35365245 http://dx.doi.org/10.1186/s41232-022-00197-8 |