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Combined immunization with inactivated vaccine reduces the dose of live B. abortus A19 vaccine

BACKGROUND: Brucella spp. is an important zoonotic pathogen responsible for brucellosis in humans and animals. Brucella abortus A19 strain is a widespread vaccine in China. However, it has a drawback of residual virulence in animals and humans. METHODS: In this study, the BALB/c mice were inoculated...

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Detalles Bibliográficos
Autores principales: He, Chuan-Yu, Zhang, Yu-Zhuo, Liu, Meng-Zhi, Zhao, Hai-Long, Ren, Li-Song, Liu, Bao-Shan, He, Sun, Chen, Ze-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976406/
https://www.ncbi.nlm.nih.gov/pubmed/35366881
http://dx.doi.org/10.1186/s12917-022-03229-0