The GPIb-IX complex on platelets: insight into its novel physiological functions affecting immune surveillance, hepatic thrombopoietin generation, platelet clearance and its relevance for cancer development and metastasis

The glycoprotein (GP) Ib-IX complex is a platelet receptor that mediates the initial interaction with subendothelial von Willebrand factor (VWF) causing platelet arrest at sites of vascular injury even under conditions of high shear. GPIb-IX dysfunction or deficiency is the reason for the rare but s...

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Detalles Bibliográficos
Autores principales: Bendas, Gerd, Schlesinger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976409/
https://www.ncbi.nlm.nih.gov/pubmed/35366951
http://dx.doi.org/10.1186/s40164-022-00273-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976409/
https://www.ncbi.nlm.nih.gov/pubmed/35366951
http://dx.doi.org/10.1186/s40164-022-00273-2

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