Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation

BACKGROUND: Many patients with diabetes die from diabetic cardiomyopathy (DCM); however, effective strategies for the prevention or treatment of DCM have not yet been clarified. METHODS: Leptin receptor-deficient (db/db) mice were treated with either the soluble epoxide hydrolase (sEH) inhibitor AUD...

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Detalles Bibliográficos
Autores principales: Fang, Qin, Liu, Xiaohui, Ding, Jie, Zhang, Zhihao, Chen, Guangzhi, Du, Tingyi, Wang, Yan, Xu, Renfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976467/
https://www.ncbi.nlm.nih.gov/pubmed/35378826
http://dx.doi.org/10.1155/2022/3773415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976467/
https://www.ncbi.nlm.nih.gov/pubmed/35378826
http://dx.doi.org/10.1155/2022/3773415

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