Chalcone Derivatives as Potential Inhibitors of P-Glycoprotein and NorA: An In Silico and In Vitro Study

The human P-glycoprotein (P-gp) and the NorA transporter are the major culprits of multidrug resistance observed in various bacterial strains and cancer cell lines, by extruding drug molecules out of the targeted cells, leading to treatment failures in clinical settings. Inhibiting the activity of t...

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Detalles Bibliográficos
Autores principales: Le, Minh-Tri, Trinh, Dieu-Thuong Thi, Ngo, Trieu-Du, Tran-Nguyen, Viet-Khoa, Nguyen, Dac-Nhan, Hoang, Tung, Nguyen, Hoang-Minh, Do, Tran-Giang-Son, Mai, Tan Thanh, Tran, Thanh-Dao, Thai, Khac-Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976639/
https://www.ncbi.nlm.nih.gov/pubmed/35378788
http://dx.doi.org/10.1155/2022/9982453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976639/
https://www.ncbi.nlm.nih.gov/pubmed/35378788
http://dx.doi.org/10.1155/2022/9982453

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