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Antiplatelet Activity of Tetramethylpyrazine via Regulation of the P2Y12 Receptor Downstream Signaling Pathway

BACKGROUND: Tetramethylpyrazine (TMP) is an alkaloid in Chinese herbal medicine, which possesses antiplatelet activity. TMP inhibits platelet activation in many ways. The platelet P2Y(12) receptor for adenosine 5′ diphosphate (ADP) plays a central role in platelet function, hemostasis, and thrombosi...

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Detalles Bibliográficos
Autores principales: Guan, Baoyi, Gao, Jie, Tan, Yu, Ma, Xiaojuan, Shi, Dazhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976642/
https://www.ncbi.nlm.nih.gov/pubmed/35378909
http://dx.doi.org/10.1155/2022/7941039