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Effects of Peroxiredoxin 6 and Its Mutants on the Isoproterenol Induced Myocardial Injury in H9C2 Cells and Rats

BACKGROUND: Peroxiredoxin 6 (PRDX6) is an important antioxidant enzyme, with a potential application value in the treatment of diseases caused by oxidative damage. METHODS: PRDX6 and a mutant (mPRDX6) were heterologously expressed by using an E.coli expression system and purified by Ni-affinity chro...

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Detalles Bibliográficos
Autores principales: Mu, Runhong, Ye, Siping, Lin, Rui, Li, Yupeng, Guo, Xiao, An, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976673/
https://www.ncbi.nlm.nih.gov/pubmed/35378825
http://dx.doi.org/10.1155/2022/2576310