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Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint

Treating yeast cells with the replication inhibitor hydroxyurea activates the S phase checkpoint kinase Rad53, eliciting responses that block DNA replication origin firing, stabilize replication forks, and prevent premature extension of the mitotic spindle. We previously found overproduction of Stn1...

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Detalles Bibliográficos
Autores principales: Gasparayan, Hovik, Caridi, Chris, Julius, Jeff, Feng, Wenyi, Bachant, Jeff, Nugent, Constance I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976814/
https://www.ncbi.nlm.nih.gov/pubmed/35150303
http://dx.doi.org/10.1007/s00294-022-01228-0