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Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint
Treating yeast cells with the replication inhibitor hydroxyurea activates the S phase checkpoint kinase Rad53, eliciting responses that block DNA replication origin firing, stabilize replication forks, and prevent premature extension of the mitotic spindle. We previously found overproduction of Stn1...
Autores principales: | Gasparayan, Hovik, Caridi, Chris, Julius, Jeff, Feng, Wenyi, Bachant, Jeff, Nugent, Constance I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976814/ https://www.ncbi.nlm.nih.gov/pubmed/35150303 http://dx.doi.org/10.1007/s00294-022-01228-0 |
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