Cargando…

Yeast Stn1 promotes MCM to circumvent Rad53 control of the S phase checkpoint

Treating yeast cells with the replication inhibitor hydroxyurea activates the S phase checkpoint kinase Rad53, eliciting responses that block DNA replication origin firing, stabilize replication forks, and prevent premature extension of the mitotic spindle. We previously found overproduction of Stn1...

Descripción completa

Detalles Bibliográficos
Autores principales: Gasparayan, Hovik, Caridi, Chris, Julius, Jeff, Feng, Wenyi, Bachant, Jeff, Nugent, Constance I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976814/
https://www.ncbi.nlm.nih.gov/pubmed/35150303
http://dx.doi.org/10.1007/s00294-022-01228-0

Ejemplares similares