A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk

Genome-wide association studies (GWAS) have identified many common variant loci associated with asthma susceptibility, but few studies investigate the genetics underlying moderate-to-severe asthma risk. Here, we present a whole-genome sequencing study comparing 3181 moderate-to-severe asthma patient...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Diana, Hunkapiller, Julie, Bhangale, Tushar, Reeder, Jens, Mukhyala, Kiran, Tom, Jennifer, Cowgill, Amy, Vogel, Jan, Forrest, William F., Khan, Zia, Stockwell, Amy, McCarthy, Mark I., Staton, Tracy L., Olsson, Julie, Holweg, Cecile T. J., Cheung, Dorothy S., Chen, Hubert, Brauer, Matthew J., Graham, Robert R., Behrens, Timothy, Wilson, Mark S., Arron, Joseph R., Choy, David F., Yaspan, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976834/
https://www.ncbi.nlm.nih.gov/pubmed/35368043
http://dx.doi.org/10.1038/s41598-022-09447-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976834/
https://www.ncbi.nlm.nih.gov/pubmed/35368043
http://dx.doi.org/10.1038/s41598-022-09447-8

Ejemplares similares