The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors

Renal cell carcinoma (RCC) is a kind of malignant tumor originating from the renal tubular epithelium. Approximately 30% of patients with renal cancer are found to have metastasis when first diagnosed. Exploring other effective treatment methods in addition to surgery is an urgent need in the resear...

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Detalles Bibliográficos
Autores principales: Liu, Wentao, Zhang, Bin, Zhang, Dan, Guo, Feng, Ye, Kun, Zhu, Liang, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976838/
https://www.ncbi.nlm.nih.gov/pubmed/35368029
http://dx.doi.org/10.1038/s41419-022-04760-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976838/
https://www.ncbi.nlm.nih.gov/pubmed/35368029
http://dx.doi.org/10.1038/s41419-022-04760-6

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