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Endometrial epithelial cells-derived exosomes deliver microRNA-30c to block the BCL9/Wnt/CD44 signaling and inhibit cell invasion and migration in ovarian endometriosis

Endometriosis (EMs) is a benign gynecological disorder showing some tumor-like migratory and invasive phenotypes. This study intended to investigate the role of microRNA-30c (miR-30c) in EMs, which is involved with B-cell lymphoma 9 (BCL9), an activator of the Wnt/β-catenin signaling pathway. EMs sp...

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Detalles Bibliográficos
Autores principales: Zhang, Mengmeng, Wang, Xi, Xia, Xiaomeng, Fang, Xiaoling, Zhang, Tingting, Huang, Fengying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976844/
https://www.ncbi.nlm.nih.gov/pubmed/35368023
http://dx.doi.org/10.1038/s41420-022-00941-6