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A suspension technique for efficient large-scale cancer organoid culturing and perturbation screens

Organoid cell culture methodologies are enabling the generation of cell models from healthy and diseased tissue. Patient-derived cancer organoids that recapitulate the genetic and histopathological diversity of patient tumours are being systematically generated, providing an opportunity to investiga...

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Detalles Bibliográficos
Autores principales: Price, Stacey, Bhosle, Shriram, Gonçalves, Emanuel, Li, Xiaodun, McClurg, Dylan P., Barthorpe, Syd, Beck, Alex, Hall, Caitlin, Lightfoot, Howard, Farrow, Luke, Ansari, Rizwan, Jackson, David A., Allen, Laura, Roberts, Kirsty, Beaver, Charlotte, Francies, Hayley E., Garnett, Mathew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976852/
https://www.ncbi.nlm.nih.gov/pubmed/35368031
http://dx.doi.org/10.1038/s41598-022-09508-y