Cargando…

Mathematical modelling identifies conditions for maintaining and escaping feedback control in the intestinal epithelium

The intestinal epithelium is one of the fastest renewing tissues in mammals. It shows a hierarchical organisation, where intestinal stem cells at the base of crypts give rise to rapidly dividing transit amplifying cells that in turn renew the pool of short-lived differentiated cells. Upon injury and...

Descripción completa

Detalles Bibliográficos
Autores principales: Fischer, Matthias M., Herzel, Hanspeter, Blüthgen, Nils
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976856/
https://www.ncbi.nlm.nih.gov/pubmed/35368028
http://dx.doi.org/10.1038/s41598-022-09202-z