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Mathematical modelling identifies conditions for maintaining and escaping feedback control in the intestinal epithelium
The intestinal epithelium is one of the fastest renewing tissues in mammals. It shows a hierarchical organisation, where intestinal stem cells at the base of crypts give rise to rapidly dividing transit amplifying cells that in turn renew the pool of short-lived differentiated cells. Upon injury and...
Autores principales: | Fischer, Matthias M., Herzel, Hanspeter, Blüthgen, Nils |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976856/ https://www.ncbi.nlm.nih.gov/pubmed/35368028 http://dx.doi.org/10.1038/s41598-022-09202-z |
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