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Improved Stability and Practicality for Synthesis of 4-Borono-2-[(18)F]fluoro-l-phenylalanine by Combination of [(18)O]O(2) Single-Use and [(18)F]CH(3)COOF Labeling Agents

PURPOSE: 4-Borono-2-[(18)F]fluoro-l-phenylalanine ([(18)F]FBPA) synthesized with [(18)F]F(2), produced using the (18)O(p, n)(18)F reaction, has been reported for increasing radioactivity. However, a dedicated system and complex procedure is required to reuse the costly [(18)O]O(2) gas; also, the use...

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Detalles Bibliográficos
Autores principales: Naka, Sadahiro, Watanabe, Toshimitsu, Kanai, Yasukazu, Watabe, Tadashi, Tatsumi, Mitsuaki, Kato, Hiroki, Shimosegawa, Eku, Hatazawa, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976863/
https://www.ncbi.nlm.nih.gov/pubmed/35449598
http://dx.doi.org/10.1007/s13139-021-00719-1