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Effect of transgenic Leishmania major expressing mLLO-Bax-Smac fusion gene in the apoptosis of the infected macrophages

OBJECTIVE(S): Leishmaniasis is a complex infection against which no confirmed vaccine has been reported so far. Transgenic expression of proteins involved in macrophage apoptosis-like BAX through the parasite itself accelerates infected macrophage apoptosis and prevents Leishmania differentiation. S...

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Detalles Bibliográficos
Autores principales: Aghaei, Maryam, Khanahmad, Hossein, Jalali, Akram, Aghaei, Shahrzad, Narimani, Manizheh, Hosseini, Sayed Mohsen, Namdar, Fatemeh, Hejazi, Seyed Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976903/
https://www.ncbi.nlm.nih.gov/pubmed/35432807
http://dx.doi.org/10.22038/IJBMS.2021.56960.12701