Novel oxadiazole derivatives as potent inhibitors of α-amylase and α-glucosidase enzymes: Synthesis, in vitro evaluation, and molecular docking studies

OBJECTIVE(S): Alpha-amylase and alpha-glucosidase enzyme inhibition is an effective and rational approach for controlling postprandial hyperglycemia in type II diabetes mellitus (DM). Several inhibitors of this therapeutic class are in clinical use but are facing challenges of safety, efficacy, and...

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Detalles Bibliográficos
Autores principales: Bukhari, Asma, Nadeem, Humaira, Imran, Muhammad, Muhammad, Syed Aun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976910/
https://www.ncbi.nlm.nih.gov/pubmed/35432813
http://dx.doi.org/10.22038/IJBMS.2021.58429.12977

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976910/
https://www.ncbi.nlm.nih.gov/pubmed/35432813
http://dx.doi.org/10.22038/IJBMS.2021.58429.12977

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