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Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway

PURPOSE: To investigate the effects of isotretinoin on the ocular surface and to explore the possible mechanisms. METHODS: Rats were treated with isotretinoin 20 mg/kg/d for five months and tested monthly for tear secretion, fluorescein staining, and infrared photography. After five months of treatm...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Tian, Lei, Bao, Jiayu, Li, Shang, Li, Ao, Wen, Ya, Wang, Jingyi, Jie, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8976919/
https://www.ncbi.nlm.nih.gov/pubmed/35353124
http://dx.doi.org/10.1167/iovs.63.3.29